GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs12908161 | 1 | rs35524990 | chr15:85258203 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.11 | 4.83E-5 | Schizophrenia |
| BLCA | cis | rs9475752 | 1 | rs35527216 | chr6:56791278 | BEND6 | chr6:56819773-56892138:+ | -0.27 | -3.86 | 0.000134 | Menarche (age at onset) |
| BLCA | cis | rs2243480 | 1 | rs35542501 | chr7:65431215 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.39 | 1.44E-5 | Diabetic kidney disease |
| BLCA | cis | rs9371538 | 1 | rs35564624 | chr6:151876494 | C6orf97 | chr6:151815175-151942327:+ | 0.28 | 4.1 | 5.13E-5 | Bone mineral density (spine) |
| BLCA | cis | rs2120019 | 1 | rs35577967 | chr15:75354621 | SCAMP5 | chr15:75287901-75313836:+ | 0.28 | 4.71 | 3.5E-6 | Blood trace element (Zn levels) |
| BLCA | cis | rs7927771 | 1 | rs35624992 | chr11:47615798 | C1QTNF4 | chr11:47611216-47615961:- | -0.29 | -5.62 | 3.78E-8 | Subjective well-being |
| BLCA | cis | rs12908161 | 1 | rs35630683 | chr15:85349231 | LOC388152 | chr15:84867600-84898920:- | -0.22 | -3.92 | 0.000105 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs35648189 | chr15:84740748 | LOC388152 | chr15:84867600-84898920:- | -0.26 | -4.59 | 6.03E-6 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs35658069 | chr15:84780146 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.67 | 4.27E-6 | Schizophrenia |
| BLCA | cis | rs10935120 | 1 | rs35718987 | chr3:134272783 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs35718987 | chr3:134272783 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.09 | 5.33E-5 | Height |
| BLCA | cis | rs12908161 | 1 | rs35726233 | chr15:85337800 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.16 | 4.0E-5 | Schizophrenia |
| BLCA | cis | rs6708331 | 1 | rs35734267 | chr2:70281190 | FAM136A | chr2:70523109-70529220:- | -0.26 | -4.23 | 2.87E-5 | Obesity-related traits |
| BLCA | cis | rs2243480 | 1 | rs35735127 | chr7:65300423 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.39 | 1.49E-5 | Diabetic kidney disease |
| BLCA | cis | rs1577917 | 1 | rs35760725 | chr6:86648985 | SNHG5 | chr6:86386726-86388451:- | -0.55 | -10.06 | 2.7E-21 | Response to antipsychotic treatment |